Quantitative Cordyceps Testing

Cordyceps Nucleosides

Scientific-name context: Cordyceps militaris; Ophiocordyceps sinensis (formerly Cordyceps sinensis)

Cordyceps Nucleosides covers 3 analytes with individual quantitative results for most raw materials, intermediate ingredients, and finished products.

Standard analysis uses UHPLC-DAD. MS or MS/MS analysis is available for an additional charge when ultra-low detection limits are needed.

Ordering reference: Test Code 106

Defined Coverage

One defined quantitative profile

The laboratory will confirm the matrix, reporting basis, sample requirements, timing, and price before testing begins.

3 analytes

Cordyceps Nucleosides

One quantitative panel covering cordycepin, adenosine, and HEA.

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Quantitative Coverage

Three target nucleosides

All three analytes below are individually and quantitatively reported.

  1. 01Cordycepin
  2. 02Adenosine
  3. 03N⁶-(2-Hydroxyethyl)adenosine (HEA)

Profile Rationale

Why these three Cordyceps nucleosides?

Cordycepin and adenosine are two of the primary small-molecule targets used to characterize Cordyceps ingredients and standardized products. N⁶-(2-Hydroxyethyl)adenosine (HEA) adds a third established nucleoside marker for a broader quantitative composition view.

Reporting the three compounds individually supports raw-material, culture, extract, and finished-product comparison while preserving differences among species, strains, and production systems. This profile is not an exhaustive measure of fungal bioactive constituents and does not establish efficacy.

Method & Reporting

Quantitative results in the reporting basis you need

Standard analysis

The in-house validated method runs standard on UHPLC-DAD. Every analyte listed in the profile is quantitatively reported.

Optional sensitivity

MS or MS/MS analysis is available for an additional charge when a project requires ultra-low detection limits. Confirm feasibility and pricing before submission.

Reporting units

The default unit is w/w%. Results may also be reported as mg/g, mg/mL, or mg/unit when the submission supports the requested basis.

Matrices & Sample Quantity

Raw materials through finished products

Most raw materials, intermediate ingredients, and finished products are supported. Matrix-specific preparation, feasibility, reporting basis, and accreditation needs are confirmed during intake. Call or email the laboratory before submitting less than 2 grams.

Mass-basis reporting

For samples under 2 grams, contact the laboratory before shipping so feasibility can be confirmed.

mg/mL reporting

Send at least 5 mL when results are requested on a volume basis.

mg/unit reporting

Send at least 5 individual units or servings when results are requested per unit.

Turnaround

Five business days standard

Expedited turnaround as fast as 12 hours may be available for an additional fee. Call or email the laboratory for feasibility and the detailed expedite fee schedule.

Have a time-sensitive project?

Include the matrix, sample count, requested reporting units, and deadline so the laboratory can evaluate the fastest available schedule.

Quality Context

Validated in-house

The method is validated in-house. Cora Science is accredited in the field of testing to ISO/IEC 17025:2017 by Perry Johnson Laboratory Accreditation, Inc. (PJLA), Accreditation #116374.

Accreditation applies only to activities listed in the laboratory's current accreditation scope; not every service or matrix is necessarily within scope. State any project-specific accreditation requirement during quote review.

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Market & Specification Context

Document the species and production material

Cordyceps nucleoside composition can vary with species, strain, production conditions, and material type. Provide the exact labeled species, production context, specification, and reporting basis during intake.

Published cordycepin context

Published cordycepin reports include the species below. Reports for Isaria cicadae / Cordyceps cicadae and Ophiocordyceps sinensis (formerly Cordyceps sinensis, including Hirsutella sinensis cultures) are inconsistent across strains and analytical methods.

  • Cordyceps militaris
  • Cordyceps kyushuensis
  • Cordyceps pruinosa
  • Cordyceps nidus
  • Cordyceps tenuipes (formerly Isaria tenuipes)
  • Cordyceps guangdongensis
  • Ophiocordyceps formosana
  • Samsoniella hepiali (formerly Paecilomyces hepiali)
  • Keithomyces neogunnii (formerly Metacordyceps neogunnii and historically misidentified as Cordyceps gunnii in some literature)

Submission and specification

State whether the sample is fruiting body, cultured mycelium, fermentation material, an extract or intermediate ingredient, a blend, or a finished product. Identify whether limits apply to cordycepin, adenosine, HEA, a combined result, or another separately defined calculation.

Analytical scope

This three-analyte composition profile does not identify or authenticate fungal species, distinguish fruiting body from mycelium, determine growth substrate, establish efficacy, or certify product compliance. Its calculated result represents only the three named analytes, not total nucleosides or total bioactive content.

FAQ

Planning a submission

What does Cordyceps Nucleosides report?

Cordyceps Nucleosides covers the 3 analytes listed on this page with quantitative reporting. Share any project-specific specification or reporting convention during quote review.

What matrices can be submitted?

Most raw materials, intermediate ingredients, and finished products are supported. Unusual formats, samples below two grams, and matrix-specific reporting or accreditation requests should be discussed with the laboratory before submission.

What reporting units are available?

The default is weight by weight percent (w/w%). Reporting may also be requested as mg/g, mg/mL, or mg/unit when the submission supports the requested basis.

How quickly are results available?

Standard turnaround is five business days. Expedited turnaround as fast as 12 hours may be available for an additional fee after the laboratory confirms feasibility.

Next Step

Request Cordyceps Nucleosides and share the matrix.